Introduction: Acetaminophen (APAP) toxicity is the main cause of acute liver failure in the United States. A prior series (1992-1995) identified 71 hospitalized adults with APAP toxicity through the International Statistical Classification of Disease and Related Health Problems, 9th revision (ICD-9) code at Parkland Hospital, Dallas, TX.
Methods: We used a laboratory database search of serum APAP levels from 2011 to 2015 to identify patients with APAP toxicity in the same hospital.
Results: We identified 140 patients hospitalized for APAP toxicity from 27,143 APAP levels obtained; 35 required Intensive Care Unit (ICU) admission, and there were no deaths. APAP toxicity/100,000 admissions was similar between eras.
Discussion: APAP toxicity continues unabated after 20 years but with improved overall outcomes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662680 | PMC |
| http://dx.doi.org/10.14309/ajg.0000000000001826 | DOI Listing |
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