The autologous fat injection technique, called lipofilling or lipomodeling, is used in both aesthetic and reconstruction procedures. Lipofilling is rarely accompanied by complications. We report the case of a young female patient who had undergone breast lipofilling before and who developed significant recurrent but self-limiting inflammatory mastitis in the previously injected breast during two successive pregnancies. To our knowledge, no case of post-lipofilling inflammatory mastitis induced by pregnancy has been described to date. This case suggests an interaction between autologous fat injected into the breast and hormonal impregnation linked to pregnancy. This interaction would create a local environment conducive to the occurrence of an inflammatory reaction, according to a pathophysiological mechanism yet to be defined.
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