Chronic Non-Healing Ulcers Associated with Atopic Inflammation: A Case Report.

Clin Cosmet Investig Dermatol

Department of Dermatology, Southwest Hospital, Army Medical University, Chongqing, People's Republic of China.

Published: July 2022

AI Article Synopsis

  • Chronic non-healing ulcers result from delayed wound healing and can occur in conditions like diabetes and autoimmune diseases, but cases caused by atopic inflammation are less common.
  • A study highlighted a specific case where chronic ulcers developed after a tattoo and surgery, with atopic inflammation hindering healing.
  • Treatment with oral cyclosporine and topical creams led to stabilization of the patient's atopic condition, resulting in successful healing of the ulcers with no recurrence after three months.

Article Abstract

Chronic non-healing ulcers are the undesirable outcome of delayed wound healing influenced by many factors. It can be seen in patients with diabetes, autoimmune conditions and multiple primary skin conditions. But chronic non-healing ulcers secondary to atopic inflammation are rarely reported in the literature. In this study, we reported a case with wounds caused by the wrong tattoo and surgery, activation of atopic inflammation caused delayed wound healing and the formation of chronic non-healing ulcers. The patient's atopic inflammation was relieved and stabilized with oral cyclosporine and topical application of halometasone cream and subsequently 0.1% tacrolimus cream, and then the chronic non-healing ulcers healed well, without recurrence at a follow-up visit 3 months later.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341257PMC
http://dx.doi.org/10.2147/CCID.S374964DOI Listing

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