Meningiomas are tumors arising from leptomeninges. Malignant counterpart of them is known as anaplastic meningioma which are WHO grade III tumors. Intraventricular location of these tumors is rare and is clinic-radiologically challenging. Histopathology and immunohistochemistry are confirmatory. We present case of a 27-year-old girl, who presented with usual symptoms of intraventricular mass in emergency. After shunt surgery, clinical diagnosis of ependymoma was formed with differential of high-grade glioma. Squash tissue was difficult to crush displaying tight clusters of spindle cells with necrosis in background. Definitive histology revealed high grade spindle cell neoplasm disposed in sheets with brisk and atypical mitosis. Only focal whorling pattern was seen. Large cells with eccentric cytoplasm, reminiscent of rhabdoid cells were also seen. Immunohistochemistry was positive for vimentin and EMA, negative for GFAP. Final diagnosis of Anaplastic meningioma was dispatched. The histological pattern of the present case, young age of presentation and presence of Rhabdoid cells make it unusual. Though rare but intraventricular meningiomas must also be kept in clinical radiological differentials apart from the usual ependymoma at this location.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340328 | PMC |
| http://dx.doi.org/10.1177/2632010X221115157 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Locally advanced nasopharyngeal follicular dendritic cell sarcoma misdiagnosed as meningioma.
Discov Oncol
January 2025
Pathology Department, Salah Azeiz Institute, 1006, Tunis, Tunisia.
Follicular dendritic cell sarcoma (FDCS) is a rare malignancy, often challenging to diagnose due to its nonspecific presentation and resemblance to other neoplasms. This case highlights a locally advanced nasopharyngeal FDCS initially misdiagnosed as a meningioma, underscoring the importance of differential diagnosis in unusual tumor presentations. A 77-year-old patient presented with nasal obstruction for 3 months.
View Article and Find Full Text PDFPrognostic factors for first recurrence following meningioma surgery.
Med Int (Lond)
December 2024
Department of Neurosurgery, School of Medicine, University of Ioannina, 45500 Ioannina, Greece.
The present study investigated the role of the Simpson grade system, MIB-1 immunohistochemical marker, meningioma location and grade in the risk of recurrence. Between January, 2008 and January, 2018, the present study retrospectively evaluated all patients undergoing craniotomy for the resection of a histopathologically confirmed meningioma. Patients with neurofibromatosis, acoustic neurinomas and radiation treatment prior to surgery were excluded.
View Article and Find Full Text PDFADC histogram analysis of tumor-infiltrating CD8+ T cell levels in meningioma.
Neurosurg Rev
January 2025
Department of Radiology, Lanzhou University Second Hospital, Lanzhou, 730030, China.
To investigate the value of preoperative MRI features and ADC histogram analysis for evaluating tumor-infiltrating CD8+ T cells in meningiomas. In this single-center cross-sectional study, we conducted a retrospective analysis of clinical, imaging, and pathological data from 84 patients with meningioma and performed immunohistochemical staining to quantitatively evaluate CD8+ T cells. Using X-Tile software, we divided the patients into high-and low-CD8+ T cells groups based on cut-off values.
View Article and Find Full Text PDFThe "Outline Sign": Thin Hyperenhancing Perimeter as an MR Imaging Feature of Meningioma. A Useful Tool in the Temporal Bone Region for Differentiating Meningiomas from Schwannomas and Paragangliomas.
AJNR Am J Neuroradiol
January 2025
Department of Radiology (K.L.R, L.V.R., A.F.J.), Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts
Background And Purpose: This study investigates the practicality and utility of the "outline sign," which refers to the thin curvilinear hyperenhancing line that may be seen along the margin of a meningioma on a spin-echo postcontrast T1-weighted image. For cases in which the differential diagnosis may include other tumors, visualization of the outline sign may help to increase the diagnostic confidence for a meningioma. Therefore, in the temporal bone region such as the cerebellopontine angle or jugular foramen, where differential considerations may include a schwannoma or paraganglioma, we additionally investigated whether the outline sign may be observed in these nonmeningioma lesions.
View Article and Find Full Text PDFDelayed Development of a Giant Cranial Pseudomeningocele After Surgical Excision of a Parasagittal Meningioma: A Case Report.
Cureus
December 2024
Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, IND.
Pseudomeningoceles are among the most common postoperative neurosurgical complications, usually presenting in the early postoperative period and often responding well to nonsurgical management. Here, we present a case of a giant cranial pseudomeningocele that developed three years after parasagittal meningioma resection, without any known risk factors. Despite conservative measures, the pseudomeningocele grew significantly over two years, reaching 22 cm along its long axis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!