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Iodine-catalyzed synthesis of benzoxazoles using catechols, ammonium acetate, and alkenes/alkynes/ketones C-C and C-O bond cleavage. | LitMetric

An efficient metal-free synthesis strategy of benzoxazoles was developed coupling catechols, ammonium acetate, and alkenes/alkynes/ketones. The developed methodology represents an operationally simple, one-pot and large-scale procedure for the preparation of benzoxazole derivatives using molecular iodine as the catalyst.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302334PMC
http://dx.doi.org/10.1039/d2ra03340bDOI Listing

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