We developed daily maps of surface fine particulate matter (PM) for the western United States. We used geographically weighted regression fit to air quality station observations with Moderate Resolution Imaging Spectroradiometer (MODIS) aerosol optical depth (AOD) data, and meteorological data to produce daily 1-kilometer resolution PM concentration estimates from 2003-2020. To account for impacts of stagnant air and inversions, we included estimates of inversion strength based on meteorological conditions, and inversion potential based on human activities and local topography. Model accuracy based on cross-validation was R = 0.66. AOD data improve the model in summer and fall during periods of high wildfire activity while the stagnation terms capture the spatial and temporal dynamics of PM in mountain valleys, particularly during winter. These data can be used to explore exposure and health outcome impacts of PM across spatiotemporal domains particularly in the intermountain western United States where measurements from monitoring station data are sparse. Furthermore, these data may facilitate analyses of inversion impacts and local topography on exposure and health outcome studies.
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http://dx.doi.org/10.1038/s41597-022-01488-y | DOI Listing |
Exp Neurol
December 2024
Department of Pediatrics, Rainbow Babies & Children's Hospital, Case Western Reserve University, Cleveland, OH, United States of America. Electronic address:
Neonatal sepsis results in significant morbidity and mortality, but early detection is clinically challenging. In a neonatal rat model of endotoxic shock, we identified unique infrared thermographic (IRT) profiles in skin temperature that could identify risk of later mortality. Ten-day old rats were placed in a thermally stable isolette and IRT images of cranial (T), scapula (T) and rump (T) skin temperature were obtained continuously for 8 h following an intraperitoneal injection of LPS (or saline).
View Article and Find Full Text PDFInt J Sports Physiol Perform
December 2024
School of Health Sciences, Western Sydney University, Campbelltown, NSW, Australia.
Purpose: The present study investigated the effect of unpleasant salty or bitter tastes on cycling sprint performance and knee-extensor force characteristics in different fatigue states.
Methods: Following a familiarization session, 11 trained male cyclists completed 3 experimental trials (salty, bitter, and water) in a randomized crossover order. In each trial, participants cycled at 85% of the respiratory compensation point for 45 minutes and then, after a 5-minute rest, completed a 1-minute sprint.
J Agric Food Chem
December 2024
Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Yuanmingyuan West Road, Beijing 100193, China.
In clinical mastitis of dairy cows, the abnormal accumulation of apoptotic cells (ACs) and subsequent secondary necrosis and inflammation pose significant concerns, with macrophage-mediated efferocytosis, crucial for ACs clearance, remaining unexplored in this context. In nonruminants, MER proto-oncogene tyrosine kinase (MERTK) receptors are essential for efferocytosis and A Disintegrin and Metalloproteinase 17 (ADAM17) is thought to play a role in regulating MERTK integrity. This study aimed to delineate the in situ role of efferocytosis in clinical mastitis, with a particular focus on the interaction between MERTK and ADAM17 in bovine macrophages.
View Article and Find Full Text PDFVet Comp Orthop Traumatol
December 2024
Surgery Department, Evidensia Dierenziekenhuis Hart van Brabant, Waalwijk, Brabant, The Netherlands.
Objective: To describe percutaneous fluoroscopy-guided placement of self-drilling, self-tapping, 3.0 mm cannulated headless compression screws (HCS) for surgical reduction of sacroiliac luxation (SIL) in cats, and to document clinical outcome.
Materials And Methods: Medical records of cats with SIL, managed by percutaneous fluoroscopy-guided placement of a 3.
J Mech Behav Biomed Mater
December 2024
Department of Prosthodontics, Dental and Craniofacial Bioengineering and Applied Biomaterials, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece. Electronic address:
Introduction: Α customized organ-on-a-chip microfluidic device was developed for dynamic culture of oral mucosa equivalents (Oral_mucosa_chip-OMC).
Materials And Methods: Additive Manufacturing (AM) was performed via stereolithography (SLA) printing. The dimensional accuracy was evaluated via microfocus computed tomography (mCT), the surface characteristics via scanning electron microscopy (SEM), while the mechanical properties via nanoindentation and compression tests.
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