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Effect of Autogenous Auricular Cartilage Composite Skin Graft for Bilateral Cleft Lip Nose Deformity Repair.
J Craniofac Surg
December 2024
Department of Plastic Surgery, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, China.
Objective: Bilateral cleft lip nose deformity often involves nasal alar retraction. The use of autogenous auricular cartilage for correction further aggravated nasal alar retraction caused by nasal lining defects after the operation. A novel graft was developed to address bilateral cleft lip nose deformity.
View Article and Find Full Text PDFEnhancement of Chondrogenic Differentiation in Bone Marrow-Derived Stem Cell Spheroids by Methanolic Extract: Insights into Concentration-Dependent mRNA Expression and Gene Clustering Analysis.
J Pers Med
December 2024
Department of Medicine, Graduate School, The Catholic University of Korea, Seoul 06591, Republic of Korea.
: L. has been utilized as a medicinal plant for centuries. This research sought to examine the effects of cumin methanolic extract (CMT) on the chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells.
View Article and Find Full Text PDFAdvances in the Development of Auricular Cartilage Bioimplants.
Tissue Eng Part B Rev
December 2024
Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Mexico.
Conditions such as congenital abnormalities, cancer, infections, and trauma can severely impact the integrity of the auricular cartilage, resulting in the need for a replacement structure. Current implants, carved from the patient's rib, involve multiple surgeries and carry risks of adverse events such as contamination, rejection, and reabsorption. Tissue engineering aims to develop lifelong auricular bioimplants using different methods, different cell types, growth factors and maintenance media formulations, and scaffolding materials compatible with the host.
View Article and Find Full Text PDFFabrication of a three-dimensional scaffold-free trachea with horseshoe-shaped hyaline cartilage: Comment.
Eur J Cardiothorac Surg
December 2024
Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences Saveetha University India.
Evaluation of Bioprinted Autologous Cartilage Grafts in an Immunocompetent Rabbit Model.
Adv Ther (Weinh)
June 2024
Department of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty Mannheim, University of Heidelberg, Germany; Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Mannheim, University of Heidelberg, Germany.
The gold standard of auricular reconstruction involves manual graft assembly from autologous costal cartilage. The intervention may require multiple surgical procedures and lead to donor-site morbidity, while the outcome is highly dependent on individual surgical skills. A tissue engineering approach provides the means to produce cartilage grafts of a defined shape from autologous chondrocytes.
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