[COVID-19 with strange hallucinations and focal EEG abnormalities: Two case reports].

Ideggyogy Sz

Debreceni Egyetem Klinikai Központ, Kenézy Gyula Campus, Neurológiai Osztály, Debrecen.

Published: July 2022

Scientific literature about the ongoing COVID-19 disease and pandemic is considerable, though articles concentrate on the severe cases and their central nervous system manifestations. This article demonstrates two cases: middle-aged female patients who had serologically proven SARS-CoV-2 infection with mild upper airway and central nervous system symptoms. The patients reported vivid, strange, simple, and complex visual and auditory hallucinations. A characteristic element of these complex hallucinations was a talking human-shaped figure. Only three similar cases have been published; this article discusses common features of all five patients. This summary highlights that in COVID-19 cases, minor central nervous system symptoms can accompany mild or even missing upper respiratory symptoms. The cranial MRIs of the presented patients were normal, but the EEG showed focal abnormalities in localizations related to hallucinations, which emphasizes the importance of EEG in differential diagnostic procedures.

Download full-text PDF

Source
http://dx.doi.org/10.18071/isz.75.0284DOI Listing

Publication Analysis

Top Keywords

central nervous
12
nervous system
12
system symptoms
8
[covid-19 strange
4
hallucinations
4
strange hallucinations
4
hallucinations focal
4
focal eeg
4
eeg abnormalities
4
abnormalities case
4

Similar Publications

Central nervous system hemangioblastoma (CNS-HB) is the most common manifestation of von Hippel-Lindau disease (VHL). The main axis of the CNS-HB pathway is the VHL-HIF signaling pathway. Recently, we proposed an alternative VHL-JAK-STAT pathway in CNS-HB.

View Article and Find Full Text PDF

Exosomes: new targets for understanding axon guidance in the developing central nervous system.

Front Cell Dev Biol

January 2025

Key Laboratory of Tropical Translational Medicine and Ministry of Education, Hainan Academy of Medical Sciences, Hainan Medical University, Haikou, China.

Axon guidance is a key event in neural circuit development that drives the correct targeting of axons to their targets through long distances and unique patterns. Exosomes, extracellular vesicles that are smaller than 100 nm, are secreted by most cell types in the brain. Regulation of cell-cell communication, neuroregeneration, and synapse formation by exosomes have been extensively studied.

View Article and Find Full Text PDF

Objective: This study aimed to elucidate the clinical manifestations, laboratory findings and outcomes of patients with intravascular large B cell lymphoma (IVLBCL) with neurological involvement and to differentiate IVLBCL with and without neurological involvement.

Methods: A cohort study was conducted at Siriraj Hospital, Mahidol University, Thailand, between January 2005 and September 2024. Clinical data, laboratory values and central nervous system imaging results were analysed.

View Article and Find Full Text PDF

Older patients represent a unique and vulnerable subgroup, requiring careful consideration when determining treatment options. Treatment-related leukoencephalopathy is commonly observed in older patients months to years after receiving radiotherapy and/or methotrexate for primary central nervous system lymphoma (PCNSL). Tirabrutinib is an orally available, highly selective, and potent second-generation Bruton's tyrosine kinase inhibitor (BTKi) approved for treating recurrent/refractory PCNSL in Japan.

View Article and Find Full Text PDF

Retinal ganglion cells (RGCs) generally fail to regenerate axons, resulting in irreversible vision loss after optic nerve injury. While many studies have shown that modulating specific genes can enhance RGCs survival and promote optic nerve regeneration, inducing long-distance axon regeneration through single-gene manipulation remains challenging. Nevertheless, combined multi-gene therapies have proven effective in significantly enhancing axonal regeneration.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!