Clinical case: Serpiginous-like choroiditis with macular involvement and good response after treatment with adalimumab.

Arch Soc Esp Oftalmol (Engl Ed)

IOBA (Instituto de Oftalmobiología Aplicada), Universidad Valladolid, Hospital Universitario de Valladolid, Valladolid, Spain.

Published: August 2022

AI Article Synopsis

  • A 42-year-old woman experienced decreased vision in her left eye due to multifocal choroiditis, prompting various diagnostic tests, including a vitrectomy, which ruled out infections but identified a positive QuantiFERON® test.
  • She was diagnosed with serpeginous-like choroiditis (SLC) and started on anti-tuberculosis treatment, but her vision worsened due to the ongoing inflammation.
  • Once conventional immunotherapy and biological treatments were added, her vision significantly improved, highlighting the importance of addressing both the infection and inflammatory components in SLC treatment.

Article Abstract

Clinical case of a 42-year-old woman who consulted for decreased vision in the left eye over two months, associated with multifocal choroiditis. Different diagnostic tests were performed to rule out infectious pathologies, as well as a diagnostic vitrectomy test, which was negative. QuantiFERON® was found to be positive and a diagnosis of serpeginous-like choroiditis (SLC) was made. Anti-tuberculosis treatment was started with worsening of vision and multifocal choroiditis. Once conventional immunotherapy and biological treatment were added, the patient presented a significant improvement in vision. To conclude, in cases of CSL, it is not only necessary to treat the infection but also the inflammatory component either with steroids or conventional immunotherapy or immunosuppression with biologics, thus reducing the number of reactivations and improving the visual prognosis.

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Source
http://dx.doi.org/10.1016/j.oftale.2021.02.011DOI Listing

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