A 45-year-old Japanese man underwent esophagogastroduodenoscopy, which revealed spotty redness at the gastric fornix, mucosal swelling, diffuse redness in the corpus, and mucosal atrophy in the gastric angle and antrum. Histological examination showed rod-shaped bacteria that appeared larger than . The patient tested positive for rapid urease test, and serum anti- IgG antibody test results were negative. Further examination of the bacteria revealed that antibody test was positive, and the presence of was confirmed using -specific real-time PCR. was successfully eradicated after triple therapy with vonoprazan, amoxicillin, and clarithromycin. This case reinforces the notion that non- Helicobacter species such as and may be involved in the pathogenesis of active gastritis in patients who test negative for antibodies.
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| http://dx.doi.org/10.1155/2022/4254605 | DOI Listing |
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