Objective: To compare the analgesic efficacy and safety of paracervical block and conscious sedation in the surgical evacuation of the uterus following a first-trimester miscarriage.
Methods: This is an open-label, randomised control trial comparing pain relief by paracervical block versus conscious sedation during manual vacuum aspiration of first-trimester incomplete miscarriages. One-hundred and sixty-two women were equally randomised into two groups. Group A (paracervical group) received a paracervical block of 4 ml of lidocaine each at the 4 and 8 o'clock positions. Group B (conscious sedation group) received intravenous 30 mg pentazocine and 10 mg diazepam. Data obtained were presented using a frequency table, student t-test, chi-square and Mann-Whitney test and bar chart. A P-value of ⩽0.05 was taken to be statistically significant.
Results: The mean pain score was lower in the paracervical block group compared to the conscious sedation group (P < 0.05); however, there was no significant difference in women's satisfaction between the groups (P ⩾ 0.05). Conscious sedation had more negative side effects compared to paracervical block which was significant (P < 0.05).
Conclusion: Paracervical block has better pain control compared with conscious sedation and has a good side effect profile.
Trial Registration: Pan African Clinical Trial Registry (registered trial no. PACTR202108841661192).
Synopsis: Paracervical block for manual vacuum aspiration (MVA) during first-trimester miscarriage is associated with less pain among women compared with conscious sedation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326839 | PMC |
| http://dx.doi.org/10.1177/20503121221113227 | DOI Listing |
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