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http://dx.doi.org/10.1016/j.visj.2022.101479 | DOI Listing |
Anal Chem
December 2024
NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
A simple, rapid, and visual approach is developed to perform diagnosis of urinary tract infection (UTI) and antimicrobial susceptibility testing (AST) by employing smart bifunctional DNA (bfDNA) sensors, exonuclease III, concatermers of CuO nanoparticles (CuONPs), and gold NPs (AuNPs) aggregation [AuNPs agglutination (AA)], namely, the bfDEC-AA method. The bfDNA sensors serve as probes for identifying 16S rRNA genes of bacterium or 18S rRNA of fungus and as mediators connecting the concatermers of CuONPs. The AA as a signal source is triggered by Cu(I)-catalyzed azide-alkyne cycloaddition click chemistry.
View Article and Find Full Text PDFInt J STD AIDS
December 2024
Department of Dermatology, Venereology and Leprology, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, India.
Dermoscopy is a non-invasive tool which helps in the visualization of skin structures and patterns not visible to the naked eye. This study evaluates the effectiveness of dermoscopy in diagnosing primary syphilis, which typically presents as a painless ulcer at the site of inoculation. In this study, dermoscopic patterns such as vascular structures and background colour changes were analyzed in patients with confirmed primary syphilis.
View Article and Find Full Text PDFCogn Process
December 2024
Department of Psychology, National Research University Higher School of Economics, Moscow, Russia.
As technological interfaces are relatively new cultural tools, regular interaction can lead to new psychological phenomena, like the baby duck syndrome, where users favor old interfaces over updates. This syndrome is seen as a cognitive bias in human-computer interaction. Two studies were conducted: Study 1 on an Airbnb app (old vs.
View Article and Find Full Text PDFTech Innov Patient Support Radiat Oncol
December 2024
Sapporo Kojinkai Memorial Hospital, Sapporo High Functioning Radiotherapy Center, 1-16-1 Miyanosawa 2-jo, Nishi-ku, Sapporo-shi, Hokkaido 063-0052, Japan.
Anticipating the onset, location and severity of radiation dermatitis before radiotherapy can aid in dermatological care. This study developed a method for creation of a prediction diagram for dermatitis and conducted a comparative verification between the prediction diagram and actual patient condition. The prediction diagram involved converting skin doses into 2 Gy fractionated equivalent doses using α/β of 10.
View Article and Find Full Text PDFClin Chem Lab Med
December 2024
Clinical Biochemistry Department, Harrogate NHS Foundation Trust, Harrogate, UK.
Objectives: Accurate assessment of calcium levels is crucial for optimal management of regular Haemodialysis (HD) patients. Different calcium adjustment equations and albumin methods; including bromocresol purple (BCP) and bromocresol green (BCG) assays are employed by laboratories, which cause considerable discrepancies between reported results. The aim of this study is to assess the influence of albumin assays on calcium status in stable haemodialysis patients against free calcium (fCa) as a gold standard test.
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