Purpura is provoked when the affected area is warmed up to 40 degrees C by means of an infrared lamp in cryoglobulinemia after exposition to cold with consecutive urticaria. For this way of causing purpura in two steps, we suggest the designation "bithermo-test".

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Purpura is provoked when the affected area is warmed up to 40 degrees C by means of an infrared lamp in cryoglobulinemia after exposition to cold with consecutive urticaria. For this way of causing purpura in two steps, we suggest the designation "bithermo-test".

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Report on a female patient suffering from cold urticaria and cold purpura in cryoglobulinemia. The process of diagnosis and further clinical investigation (bithermotest) are described.

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