A survey was performed of that rare hematological disease with a diagnostic therapeutic purpose. A case is reported with hairy-cell leukemia diagnosed while living, with the description of the clinical signs, morphological, cytochemical and immunohematological characteristics of hairy-cell leukemia. The diagnosis was confirmed by trephine biopsy, electron microscopy and pathomorphological study on the spleen. Good results are reported from splenectomy after 2-year observation.
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