Summary: Bioinformatics applications increasingly rely on ad hoc disk storage of k-mer sets, e.g. for de Bruijn graphs or alignment indexes. Here, we introduce the K-mer File Format as a general lossless framework for storing and manipulating k-mer sets, realizing space savings of 3-5× compared to other formats, and bringing interoperability across tools.
Availability And Implementation: Format specification, C++/Rust API, tools: https://github.com/Kmer-File-Format/.
Supplementary Information: Supplementary data are available at Bioinformatics online.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477520 | PMC |
| http://dx.doi.org/10.1093/bioinformatics/btac528 | DOI Listing |
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