What are potential causes of Marjolin ulcer and how do they present?How are MU diagnosed?What are differential diagnoses for MU, and what can help differentiate them?What are the appropriate treatments for MU?
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Oncologist
December 2024
Oncology Division, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Background: Cutaneous squamous cell carcinoma (cSCC) is characterized by a high tumor mutational burden due to solar damage and a favorable response to anti-PD-1 immunotherapy. Yet, we encounter tumors arising in areas with minimal sun exposure, such as cSCC that develops in chronically inflamed skin, also known as Marjolin's Ulcer (MU). The response of MU-SCC to immunotherapy remains unknown.
View Article and Find Full Text PDFIndian J Surg Oncol
December 2024
Biostatistics & Health Informatics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Inguinal skin flap necrosis (SFN) is a significant clinical problem associated with inguinal lymph node dissection (ILND). The aetiology of SFN is multifactorial, and its manifestations vary widely. Thermal damage caused by electrocautery during the elevation of the skin flap may contribute to this problem, which has not been studied previously.
View Article and Find Full Text PDFBMJ Case Rep
November 2024
Department of Dermatology, Venereology and Leprosy, Datta Meghe Institute of Higher Education and Research, Jawaharlal Nehru Medical College, Wardha, India.
A saree is a garment worn by women in the Indian subcontinent. It is usually wrapped around the body and secured over an ankle-length skirt (a petticoat). The petticoat is usually tied very tightly around the waist with a cord.
View Article and Find Full Text PDFFront Physiol
October 2024
Department of Surgery, University of Arizona, Tucson, AZ, United States.
JAAD Int
December 2024
Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
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