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Surgical Efficacy Analysis of Traumatic Posterior Fossa Epidural Hematoma in Children.
World Neurosurg
December 2024
Department of Pediatric Neurosurgery, Anhui Province Children's Hospital, Hefei, China.
Objective: To investigate the treatment effect and prognosis of posterior fossa epidural hematoma in children by different surgical methods.
Methods: The clinical data of 41 children with traumatic posterior fossa epidural hematoma treated by surgery in the Department of Neurosurgery from June 2015 to October 2023 were retrospectively analyzed. Among them, 32 cases underwent minimally invasive skull trepanation and drainage and 9 cases underwent craniotomy and hematoma removal.
A novel therapeutic pathway to the human cochlear nerve.
Sci Rep
November 2024
Department of Surgical Sciences, Otorhinolaryngology and Head and Neck Surgery, Uppsala University, Uppsala, Sweden.
Article Synopsis
- Traditional methods for accessing the human cochlear nerve are limited due to its location within the skull's bony structure.
- This study introduces a minimally invasive technique for directly reaching the cochlear nerve to apply new regenerative treatments.
- Using advanced imaging and anatomical studies, researchers identified a safe pathway to the nerve and successfully validated it on multiple human temporal bones.
Two-Photon Laser-Mediated Ablation of Osteoblasts in Developing Zebrafish Larvae.
J Vis Exp
September 2024
CRTD - Center for Regenerative Therapies TU Dresden; Center for Healthy Aging, Faculty of Medicine, TU Dresden;
Zebrafish (Danio rerio) have an outstanding capacity to regenerate different organs and appendages. Bone regeneration in zebrafish has been studied using different methods such as fin amputation, scale plucking, skull trepanation, and microscopic approaches. Using a confocal laser scanning setup equipped with a two-photon laser, a laser ablation method was developed as a lesion paradigm to ablate bone-forming cells (osteoblasts) in the developing opercle of zebrafish larvae.
View Article and Find Full Text PDFAdvancing 3-Dimensional Printed Burr Hole and Craniotomy Models for Neurosurgical Simulation Through Multimaterial Methods.
World Neurosurg
December 2024
Centre for Advanced Materials Processing and Manufacturing (AMPAM), The University of Queensland, Brisbane, Australia; School of Mechanical and Mining Engineering, Faculty of Engineering, Architecture and Information Technology, The University of Queensland, Brisbane, Australia.
Objective: Three-dimensional (3D) printing technology presents a promising avenue for the development of affordable neurosurgical simulation models, addressing many challenges related to the use of cadavers, animal models, and direct patient engagement. The aim of this study is to introduce and evaluate a new high-fidelity neurosurgical simulation model targeted for both burr hole and craniotomy procedures.
Methods: 12 different 3D-printed skull models were manufactured using 5 different materials (polyether ether ketone, White Resin, Rigid 10K, Bone, and Skull) from 3 different 3D print processes (fused filament fabrication, stereolithography [SLA], and material jetting).
The Bony Nasal Cavity and Paranasal Sinuses of Big Felids and Domestic Cat: A Study Using Anatomical Techniques, Computed Tomographic Images Reconstructed in Maximum-Intensity Projection, Volume Rendering and 3D Printing Models.
Animals (Basel)
September 2024
Department of Anatomy and Comparative Pathological Anatomy, Veterinary Faculty, University of Murcia, 30100 Murcia, Spain.
This study aims to develop three-dimensional printing models of the bony nasal cavity and paranasal sinuses of big and domestic cats using reconstructed computed tomographic images. This work included an exhaustive study of the osseous nasal anatomy of the domestic cat carried out through dissections, bone trepanations and sectional anatomy. With the use of OsiriX viewer, the DICOM images were postprocessed to obtaining maximum-intensity projection and volume-rendering reconstructions, which allowed for the visualization of the nasal cavity structures and the paranasal sinuses, providing an improvement in the future anatomical studies and diagnosis of pathologies.
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