Redifferentiation Therapy-Returning to Our Roots in a Post-Kinase Inhibitor World.

Clin Cancer Res

Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer, Houston, Texas.

Published: October 2022

Radioactive iodine (RAI) treatment is an effective treatment for differentiated thyroid cancer (DTC); however, many patients are refractory. Using targeted drugs to reinduce RAI sensitivity ("redifferentiation therapy") has long been sought after as the holy grail in endocrine oncology. See related article by Weber et al., p. 4194.

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Source
http://dx.doi.org/10.1158/1078-0432.CCR-22-1710DOI Listing

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