Effects of Heavy Metal Exposure from Leather Processing Plants on Serum Oxidative Stress and the Milk Fatty Acid Composition of Dairy Cows: A Preliminary Study.

Animals (Basel)

Milk and Dairy Product Inspection Center of the Ministry of Agriculture and Rural Affairs, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.

Published: July 2022

AI Article Synopsis

  • This study examined the impact of heavy metal exposure from leather processing on the fatty acid composition and oxidative status of cows' milk.
  • Blood lead levels in cows from a polluted area were significantly higher than those from a clean area, indicating pollution-related health risks.
  • Cows in the polluted area showed lower antioxidant enzyme levels (GST, GPX) and reduced linoleic acid content in their milk, suggesting that heavy metals may disrupt fatty acid synthesis through oxidative stress.

Article Abstract

This study investigated whether unsaturated fatty acids in milk and the oxidative status of cows are affected by heavy metal exposure due to leather processing. The blood lead (Pb) concentrations in cows from two farms in the polluted area were 16.27 ± 8.63 μg/L, respectively, which were significantly (p < 0.05) higher than the blood Pb concentrations in cows from an unpolluted farm (6.25 ± 3.04 μg/L). There were significantly (p < 0.05) lower levels of glutathione S-transferase (GST), glutathione peroxidase (GPX), and glutathione (GSH) in the serum of cows from the polluted area compared to the levels in cows from an unpolluted area. The linoleic acid (C18:2n6c) content in milk from the polluted area was 15% lower than in the control area. There was a significant correlation between linoleic acid in milk with the blood Pb and serum GSH levels. Heavy metals can alter fatty acid synthesis through oxidative stress, which may be the mechanism by which heavy metals affect fatty acid synthesis in milk.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331539PMC
http://dx.doi.org/10.3390/ani12151900DOI Listing

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