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Mechanistic insight of curcumin: a potential pharmacological candidate for epilepsy.

Front Pharmacol

January 2025

Infection and Immunity Research Strength, Jeffrey Cheah School of Medicine and Health Sciences, Monash University, Bandar Sunway, Malaysia.

Recurrent spontaneous seizures with an extended epileptic discharge are the hallmarks of epilepsy. At present, there are several available anti-epileptic drugs (AEDs) in the market. Still no adequate treatment for epilepsy treatment is available.

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Total hip arthroplasty (THA) is a highly effective surgical intervention for end-stage hip joint disorders. While common complications such as infection, dislocation, and prosthetic loosening are well-documented, rarer complications remain underreported. One such complication is foreign body interposition on the bearing surface, which can compromise joint mechanics and adversely affect outcomes.

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Harmony in healthcare: recommended infant feeding practices and associated factors among HIV positive mothers in Eastern Ethiopian hospitals.

J Health Popul Nutr

January 2025

Department of Health Promotion, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

Background: For mothers identified as HIV-infected, recommended infant feeding practices must prioritize the highest likelihood of ensuring HIV-free survival for their children while preserving maternal health. Consequently, understanding the feeding status during critical infancy stages, especially under the risk of HIV, plays a crucial role in enhancing the quality of life within this specific population segment. Hence, this study was conducted to assess the magnitude and associated factors of recommended infant feeding practices and its associated factors among HIV-positive mothers in Eastern Ethiopian Hospitals.

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Background: Female recipients of allogeneic hematopoietic stem cell transplantation are at high risk of developing human papillomavirus (HPV)-associated lesions and (pre)cancer. We describe the results of a cervical cancer screening program in these women.

Methods: From 2010 to 2022, 70 female recipients of allogeneic hematopoietic stem cell transplantation in our institution entered a standardized protocol of gynecological evaluation.

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Compromised B-cell homeostasis: Unraveling the link between major depression, infection and autoimmune disorders.

J Affect Disord

January 2025

Department of Neurology, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, China. Electronic address:

Background: Major depression can increase susceptibility to viral infections and autoimmune diseases. B cell responses are crucial for immune defense against infections but can trigger autoimmunity when deregulated. However, it remains unclear whether compromised B-cell homeostasis in major depression contributes to an increased risk of infection and autoimmunity.

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