Carbon dots (CDs) have many advantages, such as tunable photoluminescence, large two-photon absorption cross-sections, easy functionalization, low toxicity, chemical inertness, good dispersion, and biocompatibility. Halogen doping further improves the optical and physicochemical properties of CDs, extending their applications in fluorescence sensors, biomedicine, photocatalysis, anti-counterfeiting encryption, and light-emitting diodes. This review briefly describes the preparation of CDs via the "top-down" and "bottom-up" approaches and discusses the preparation methods and applications of halogen (fluorine, chlorine, bromine, and iodine)-doped CDs. The main challenges of CDs in the future are the elucidation of the luminescence mechanism, fine doping with elements (proportion, position, etc.), and their incorporation in practical devices.
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http://dx.doi.org/10.3390/molecules27144620 | DOI Listing |
Heliyon
January 2025
Transmission Electronic Microscopy Laboratory, Electronic Microscopy Unit, Department of Biology, University of Cauca, Popayán, 190002, Colombia.
A green methodology for the synthesis of carbon quantum dots (CQDs) from coffee husk without the use of any toxic solvents is proposed in this work. Sonochemical exfoliation of biochar, obtained from the thermal carbonization of coffee husk (from a certified coffee seeds) at low temperature in an air-restricted atmosphere, is described as an alternative procedure for the sustainable production of CQDs. The synthesized CQDs exhibited blue fluorescence with a strong maximum emission band at 410 nm when excited at a maximum absorption wavelength of 330 nm.
View Article and Find Full Text PDFJ Mater Chem B
January 2025
Center for Nano Science and Technology, Istituto Italiano di Tecnologia, 20134 Milano, Italy.
Carbon dots (CDs) are promising candidates as oxygen photosensitizers, in cancer therapeutic applications due to their high quantum yield, superior chemical and photostability, low cytotoxicity and ease of chemical functionalization/tuning. Nitrogen doping can further improve oxygen photosensitization performance. Besides photodynamic therapy, however, the possibility to finely and remotely regulate the intracellular redox balance by using physical stimuli has been attracting more and more interest not only for nanotheranostic application, but also as a novel, fully biocompatible therapeutic tool.
View Article and Find Full Text PDFNanoscale
January 2025
Chemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai-400085, India.
Sub-cellular organelle anomalies are frequently observed in diseases such as cancer. Early and precise diagnosis of these alterations can be crucial for patient outcomes. However, current diagnostic tools using conventional organic dyes or metal quantum dots face limitations, including poor biocompatibility, stringent storage conditions, limited solubility in aqueous media, and slow staining speeds.
View Article and Find Full Text PDFSmall
January 2025
College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 310014, P. R. China.
Developing single-particle nanocomposite with aqueous-phase orthogonal multicolor phosphorescence or multimodal luminescence holds great significance for optical coding, anti-counterfeiting encryption, bioimaging, and biosensing. However, it faces challenges such as a limited range of emission wavelengths and difficulties in controlling the synthesis process. In this work, a conjugate structure manipulation integrated luminophor confinement strategy is proposed to prepare carbon dots@upconversion nanoparticles (CDs@UCNPs) featuring aqueous-phase orthogonal multicolor room-temperature phosphorescence-upconversion luminescence (RTP-UCL) through wet-chemical synthetic methods.
View Article and Find Full Text PDFAnal Chim Acta
February 2025
Department of Chemistry and Centre of Advanced Studies in Chemistry, Panjab University, Chandigarh, 160014, India; Department of Applied Chemistry, Maulana Abul Kalam Azad University of Technology, Simhat, Haringhata, West Bengal, 741249, India. Electronic address:
Background: The intellectual progress in fabricating artificial probes for selective appraisal of biologically admissible amino acids has displayed exponential growth in recent era.The neoteric era in material science has witnessed the significant application of carbon quantum dots (CQDs). However, the hybrid microgel of CQDs was less explored.
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