Planar Optofluidic Integration of Ring Resonator and Microfluidic Channels.

Micromachines (Basel)

Institute for Electromagnetic Sensing of the Environment (IREA), National Research Council (CNR), Via Diocleziano, 328, 80124 Naples, Italy.

Published: June 2022

We report an optofluidic hybrid silicon-polymer planar ring resonator with integrated microfluidic channels for efficient liquid delivery. The device features a planar architecture of intersecting liquid-core waveguides and microfluidic channels. A low-loss integration of microfluidic channels is accomplished by exploiting the interference pattern created by the self-imaging effect in the multimode interference-based coupler waveguides. Numerical simulations have been performed in order to minimize the propagation losses along the ring loop caused by the integration of microfluidic channels. The device has been fabricated and optically characterized by measuring the quality factor, obtaining a value of 4 × 10. This result is comparable with the quality factor of an optofluidic ring with the same optical layout but without integrated microfluidic channels, thus, confirming the suitability of the proposed approach for microfluidics integration in planar optofluidic design.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315487PMC
http://dx.doi.org/10.3390/mi13071028DOI Listing

Publication Analysis

Top Keywords

microfluidic channels
24
planar optofluidic
8
ring resonator
8
integrated microfluidic
8
integration microfluidic
8
quality factor
8
microfluidic
6
channels
6
planar
4
integration
4

Similar Publications

Droplet coalescence in microchannels is a complex phenomenon influenced by various parameters such as droplet size, velocity, liquid surface tension, and droplet-droplet spacing. In this study, we thoroughly investigate the impact of these control parameters on droplet coalescence dynamics within a sudden expansion microchannel using two distinct numerical methods. Initially, we employ the boundary element method to solve the Brinkman integral equation, providing detailed insights into the underlying physics of droplet coalescence.

View Article and Find Full Text PDF

Electrochemical impedance spectroscopy has great potential for laboratory blood tests. The overall aim of this study is to develop a microfluidic sensor for determining the physical properties and hematological parameters of blood based on its dielectric spectra. Impedance was measured in flowing blood to prevent aggregation and sedimentation at frequencies between 40 Hz and 110 MHz.

View Article and Find Full Text PDF

Microfluidic Integration of Magnetically Functionalized Microwires for Flow Cytometry Protein Quantification.

Materials (Basel)

January 2025

Life Sciences Division, National Research Council of Canada, 75 de Mortagne Boulevard, Boucherville, QC J4B 6Y4, Canada.

A novel approach to protein quantification utilizing a microfluidic platform activated by a magnetic assembly of functionalized magnetic beads around soft magnetic capture centers is presented. Functionalized magnetic beads, known for their high surface area and facile manipulation under external magnetic fields, are injected inside microfluidic channels and immobilized magnetically on the surface of glass-coated soft magnetic microwires placed along the symmetry axis of these channels. A fluorescent (Cy5) immunomagnetic sandwich ELISA is then performed by sequentially flowing the sample and all necessary reagents in the microfluidic channels.

View Article and Find Full Text PDF

Interface Acoustic Waves in 128° YX-LiNbO/SU-8/Overcoat Structures.

Micromachines (Basel)

January 2025

Department of Astronautical, Electrical and Energy Engineering, University of Rome "La Sapienza", Via Eudossiana 18, 00184 Rome, Italy.

The propagation of interface acoustic waves (IAWs) in 128° YX-LiNbO/SU-8/overcoat structures was theoretically studied and experimentally investigated for different types of overcoat materials and thicknesses of the SU-8 adhesive layer. Three-dimensional finite element method analysis was performed using Comsol Multiphysics software to design an optimized multilayer configuration able to achieve an efficient guiding effect of the IAW at the LiNbO/overcoat interface. Numerical analysis results showed the following: (i) an overcoat faster than the piezoelectric half-space ensures that the wave propagation is confined mainly close to the surface of the LiNbO, although with minimal scattering in the overcoat; (ii) the presence of the SU-8, in addition to performing the essential function of an adhesive layer, can also promote the trapping of the acoustic energy toward the surface of the piezoelectric substrate; and (iii) the electromechanical coupling efficiency of the IAW is very close to that of the surface acoustic wave (SAW) along the bare LiNbO half-space.

View Article and Find Full Text PDF

A Microfluidic-Based Cell-Stretching Culture Device That Allows for Easy Preparation of Slides for Observation with High-Magnification Objective Lenses.

Micromachines (Basel)

January 2025

Department of Chemical and Biological Sciences, Faculty of Science, Japan Women's University, 2-8-1 Mejirodai, Bunkyo, Tokyo 112-8681, Japan.

Microfluidic-based cell-stretching devices are vital for studying the molecular pathways involved in cellular responses to mechanobiological processes. Accurate evaluation of these responses requires detailed observation of cells cultured in this cell-stretching device. This study aimed to develop a method for preparing microscope slides to enable high-magnification imaging of cells in these devices.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!