Periocular Infection of Complex in a Patient with Interferon-γ Autoantibodies: A Case Report.

Medicina (Kaunas)

Departments of Ophthalmology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, Taiwan.

Published: June 2022

The neutralizing anti-interferon-γ autoantibody (nAIGA)-associated immunodeficiency is an emerging entity frequently associated with the nontuberculosis mycobacterium (NTM) infection and other opportunistic infections. We present a female patient with a mysterious periocular complex (MAC) infection, accompanied by sequential opportunistic infections including and herpes zoster infection. Her condition stabilized after long-term antimycobacterial treatment. Nevertheless, neutralizing anti-interferon-γ autoantibody was found in her serum, which was compatible with the scenario of adult-onset immunodeficiency.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324542PMC
http://dx.doi.org/10.3390/medicina58070846DOI Listing

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