The aim of this study was to analyze if registered drug packs of antibiotics are in accordance with national guidelines for prostatitis treatment regard to the amount of drug units.; Methods: Croatian, UK (NICE), Australian, Spanish and Slovenian national guidelines were analyzed in this study. Results: Comparing treatment guidelines with registered drug packs resulted in perfect accordance only for drug packs registered in the UK with the NICE guidelines, where even split-pack dispensing is possible. Interestingly, when comparing drug packs registered in the UK with treatment proposed in the national guidelines of Croatia, Italy, Spain, Australia, USA and Slovenia, they matched almost perfectly. In other investigated countries, registered drug packs' national guidelines' analysis showed mismatch in 25-100% of recommendations (Italy and Slovenia, respectively). Conclusions: Mismatch between registered drug packs that are dispensed to patients and treatment guidelines may result in excess units of antimicrobials that may be misused by the patient in the future, or excess antimicrobials may become unnecessary waste, further promoting antimicrobial resistance. Greater accordance of registered drug packs of antimicrobials with treatment guidelines may lower rates of antimicrobials misuse.
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http://dx.doi.org/10.3390/healthcare10071158 | DOI Listing |
Tob Control
January 2025
Rutgers Institute for Nicotine & Tobacco Studies, New Brunswick, New Jersey, USA.
Objectives: In the USA, some tobacco companies replaced the marketing phrase '100% natural additive-free tobacco' with 'tobacco ingredients: tobacco & water' (T&W) after receiving warnings from the US Food and Drug Administration. This study assesses how people interpret the now-restricted additive-free claims and newer T&W claims on Natural American Spirit (NAS) and L&M cigarette packs.
Methods: An online between-subjects experiment randomised 2526 US adults to view one of three packs: an NAS additive-free pack, an NAS T&W pack or an L&M T&W pack.
J Chromatogr A
December 2024
Biopharm Drug Substance Development, GSK, King of Prussia, PA 19406, US.
Polymers (Basel)
November 2024
Department of Tissue Engineering and Regenerative Medicine (DTERM), Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Nasal packing is a critical procedure in postoperative care and trauma management aimed at controlling bleeding, providing structural support, and promoting tissue healing. However, conventional nasal packs often lead to discomfort, infection risks, and secondary tissue damage. To address these challenges, this study explores the potential use of biodegradable and biocompatible gelatin-carrageenan composite scaffolds as an alternative nasal packing material.
View Article and Find Full Text PDFCureus
November 2024
Trauma and Orthopaedics, Ghurki Trust Teaching Hospital, Lahore, PAK.
Introduction: Conservative treatment options, such as rest, massage, cold and heat packs, wrist splints, braces, physical therapy, thumb spica casts, and local steroid injections, have been used with mixed results to treat De Quervain's tenosynovitis. Surgical treatment, like releasing the first dorsal wrist compartment, is the last resort for resistant cases of De Quervain's tenosynovitis, exhibiting an efficacy of 91%. However, complications and increased expenses have limited the use of surgical interventions.
View Article and Find Full Text PDFSemergen
December 2024
Departamento de Especialidades Médicas y Salud Pública, Universidad Rey Juan Carlos, Alcorcón, Madrid, España.
Objective: To evaluate the impact of a medical-pharmaceutical intervention strategy on patients exposed to azathioprine-allopurinol (AZA-ALO) interaction in the Community of Madrid (CM).
Material/methods: Multicentre retrospective observational study. We reviewed the database generated after an intervention carried out in the healthcare context in which Primary Care Pharmacists (PCP) review the treatment of patients with safety risks and, when there are incidents, they contact (by telephone and/or e-mail) their Family Physicians (FP) for possible resolution.
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