Antioxidant Properties of New Phenothiazine Derivatives.

Antioxidants (Basel)

Research School of Chemistry & Applied Biomedical Sciences, National Research Tomsk Polytechnic University, 30 Lenin Avenue, 634050 Tomsk, Russia.

Published: July 2022

Phenothiazine and its derivatives have a number of properties that contribute to their wider practical use in the production of biologically active substances, drugs, dyes, etc. Therefore, the synthesis and study of new compounds is of great relevance. The aim of this work was to investigate the antioxidant activity of a number of new phenothiazine derivatives. The patterns of electroreduction of oxygen and its radicals in the presence of phenothiazine derivatives in aqueous ethanol media were studied by voltammetry. The influence of various factors on antioxidant activity was considered by the methods of experiment planning. The optimal conditions for the manifestation of the antioxidant activity of phenothiazine derivatives have been found, which seems to be relevant since it opens up new possibilities for their further use as complex preparations with antioxidant activity, including in psychiatric practice.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312155PMC
http://dx.doi.org/10.3390/antiox11071371DOI Listing

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