Objective: We investigated changes in the intestinal flora of children with pneumonia (MPP).
Methods: Between September 2019 and November 2019, stool samples from 14 children with MPP from The Fourth Hospital of Baotou city, Inner Mongolia Autonomous Region, were collected and divided into general treatment (AF) and probiotic (AFY) groups, according to the treatment of "combined and tablets live". High-throughput sequencing was used to identify intestinal flora.
Results: Intestinal flora abundance and diversity in children with MPP were decreased. Both Shannon and Simpson indices were lower in the AF group when compared with healthy controls ( < 0.05). When compared with healthy controls, the proportion of was lower in the AF group, while the proportion of was higher ( < 0.05). The proportion of and was lower in the AFY group but , , and proportions were higher. The proportion of - in the AFY group after treatment was decreased ( < 0.05).
Conclusions: The intestinal flora of children with MPP is disturbed, manifested as decreased abundance and diversity, and decreased . Our probiotic mixture partly improved intestinal flora disorders.
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