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Concomitant neuroleptic malignant syndrome and diabetes insipidus. | LitMetric

Concomitant neuroleptic malignant syndrome and diabetes insipidus.

JAAPA

At Bellevue Hospital in New York City, Carlee Zaki, Meredith Ugell, Trang Vo , and Steven Liu practice in the Department of Medicine. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Published: August 2022

AI Article Synopsis

Article Abstract

Each year, nearly one-fifth of adults in the United States are prescribed at least one psychotropic medication. An increased trend in psychiatric polypharmacy has heightened awareness of drug-drug interactions and the tracking of adverse drug reactions. This article describes a patient who developed concomitant neuroleptic malignant syndrome (NMS) and nephrogenic diabetes insipidus during cross-titration of his antipsychotics while on lithium. The patient's mild form of NMS in turn caused hypovolemia and acute kidney injury. This case study highlights the dangers of polypharmacy and how it can obscure the presentation of even classic adverse reactions.

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Source
http://dx.doi.org/10.1097/01.JAA.0000840488.74228.46DOI Listing

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