Purpose: To evaluate the effect of using a compress with infusion in the regression of dry desquamation and in the prevention of moist desquamation in head and neck cancer patients undergoing radiotherapy.
Methods: A prospective intervention study was carried out from May 2019 to May 2021. In total, 43 participants were included, who were instructed to apply the compress with the infusion 3 times a day, after occurrence of dry desquamation. Skin evaluation took place daily from initiation of the intervention up to the end of radiotherapy.
Results: All the participants presented dry desquamation regression, where 65.1% (95% CI 50.1-78.1) had total regression until the end of radiotherapy, with a mean of 9 days of regression. Only 34.9% (95% CI 21.8-49.9) of the participants developed moist desquamation by the end of the radiotherapy sessions, with a mean accumulated dose of ionizing radiation of 50.9 Gy.
Conclusion: This study highlighted the potential clinical benefits of using in the regression of dry desquamation and in the prevention of moist desquamation.
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http://dx.doi.org/10.1177/15347354221105491 | DOI Listing |
Int J Nurs Knowl
January 2025
Graduate Program in Nursing, Federal University of Ceará, Fortaleza, Brazil.
Objective: To evaluate the accuracy of the defining characteristics of the nursing diagnosis Impaired skin integrity (00046) in patients admitted to intensive care units (ICUs).
Methods: A cross-sectional diagnostic accuracy study was conducted with 105 adult patients admitted to an ICU. A latent class model with random effects was used to test the sensitivity and specificity of the defining characteristics investigated.
Sci Rep
January 2025
Institut de Radioprotection et de Sureté Nucléaire (IRSN), PSE-SANTE/SERAMED/LRAcc, 31 av de la Division Leclerc, Fontenay-aux-Roses, 92260, France.
A radiological accident may result in the development of a local skin radiation injury (LRI) which may evolve, depending on the dose, from dry desquamation to deep ulceration and necrosis through unpredictable inflammatory waves. Therefore, early diagnosis of victims of LRI is crucial for improving medical care efficiency. This preclinical study aims to identify circulating metabolites as biomarkers associated with LRI using a C57BL/6J mouse model of hind limb irradiation.
View Article and Find Full Text PDFJAMA Dermatol
January 2025
Bethesda Dermatopathology Laboratory, Silver Spring, Maryland.
Biophys J
November 2024
Skin Barrier Research Group, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic. Electronic address:
Biomed Pharmacother
November 2024
Department of Radiation Oncology, The Second Hospital of Jilin University, Changchun, Jilin 130022, China. Electronic address:
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