Objective: The aim of this study was to compare the effectiveness of supervised and unsupervised functional level-based exercises program for elderly inpatients on physical activity, mobility, health-related quality of life and depression status.
Design: A single-blinded randomised controlled trial.
Setting: Internal medicine service.
Subjects: Patients aged 65 years or older.
Interventions: A supervised functional level-based exercise program was applied to the intervention group by a physiotherapist, for 40 min 5 times a week during their hospitalisation. Patients in the control group were asked to perform an unsupervised functional level-based exercise program which was described by the physiotherapist during the first visit.
Main Measures: Mobility, physical activity level and health-related quality of life were assessed at admission and discharge in both groups. Depression status was evaluated at admission and 3 months after discharge.
Results: Sociodemographic features between intervention group ( = 62) and control group ( = 62) were similar. The intervention group showed a higher increment in mobility, physical activity level and quality of life scores than the control group ( = 0.62, < 0.05; = 0.57, < 0.05; = 1.12, < 0.05 respectively). Inpatients in the intervention group, depression scores were lower 3 months after discharge ( = 0.42, < 0.05). The length of stay in the hospital was not different between the groups.
Conclusions: A supervised functional level-based exercise program is more effective than an unsupervised functional level-based exercise program for mobility, physical activity, depression and quality of life in elderly inpatients. These positive contributions are seen within a short period like a 5 to 10 days stay in hospital.
Trial Registration: ClinicalTrials.gov(NCT03516032).
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http://dx.doi.org/10.1177/02692155221116818 | DOI Listing |
Sci Rep
December 2024
Department of Biology, Concordia University, 7141 Sherbrooke St. West, Montreal, QC, H4B 1R6, Canada.
Intraspecific variation is important for species' long-term persistence in changing environments. Conservation strategies targeting intraspecific variation often rely on the identification of management or policy units below the species level based on biological differences among populations. To identify management units, this paper examines intraspecific divergence of Lake Trout (Salvelinus namaycush) in Great Slave Lake (GSL), Canada, using low-coverage whole-genome sequencing data.
View Article and Find Full Text PDFAnn Med
December 2025
National Clinical Research Center for Kidney Diseases, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Background: In recent years, daratumumab (DARA) has gained widespread use in the treatment of systemic light chain (AL) amyloidosis. In this study, we assessed the efficacy and safety of a DARA treatment strategy based on serum free light chain (sFLC) levels and non-fixed cycles.
Methods: The study included 123 patients with Al amyloidosis who received DARA at our center between July 2020 and September 2023.
Two new species of the genus Dollmania Tams, 1930 are described: Dollmania lola sp. n. from Ivory Coast and Dollmania reggie sp.
View Article and Find Full Text PDFHeliyon
October 2024
College of Mechanical Engineering, Wuhan Polytechnic University, Wuhan, 430023, China.
In multiperson collaborative mechanical product design, unreasonable task allocation can result in excessive coupling between tasks, complex design communication, and rework, particularly in small enterprises and teams that rely primarily on experience. Hence, this study proposes a simple and efficient task-planning method based on a fuzzy design structure matrix (FDSM), which involves single-level task decomposition, three-level number assignment of the coupling relationship, decoupling of the structural tree algorithm, and validation of the optimization results based on the G-value. Design tasks are promptly allocated into a single level based on the functional structure module of the product.
View Article and Find Full Text PDFEur J Pharmacol
January 2025
Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, China; Department of Endocrinology, Renmin Hospital of Wuhan University, Wuhan, China; Cardiovascular Research Institute of Wuhan University, Wuhan, 430060, China. Electronic address:
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