Exploring the Role of in Inflammatory Diseases.

Toxins (Basel)

The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allergy & Clinical Immunology, Guangzhou Medical University, Guangzhou 510260, China.

Published: July 2022

is a very common Gram-positive bacterium, and infections play an extremely important role in a variety of diseases. This paper describes the types of virulence factors involved, the inflammatory cells activated, the process of host cell death, and the associated diseases caused by . can secrete a variety of enterotoxins and other toxins to trigger inflammatory responses and activate inflammatory cells, such as keratinocytes, helper T cells, innate lymphoid cells, macrophages, dendritic cells, mast cells, neutrophils, eosinophils, and basophils. Activated inflammatory cells can express various cytokines and induce an inflammatory response. can also induce host cell death through pyroptosis, apoptosis, necroptosis, autophagy, etc. This article discusses and MRSA (methicillin-resistant ) in atopic dermatitis, psoriasis, pulmonary cystic fibrosis, allergic asthma, food poisoning, sarcoidosis, multiple sclerosis, and osteomyelitis. Summarizing the pathogenic mechanism of provides a basis for the targeted treatment of infection.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318596PMC
http://dx.doi.org/10.3390/toxins14070464DOI Listing

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