High rates of egocentric network turnover are frequently observed but not well explained. About 1,000 respondents to the UCNets survey named an average of 10 names in each of two waves a year apart. Consistent with prior studies, respondents in wave 2 failed to relist about half of the names they provided in wave 1. Asked why, respondents explained that they had forgotten the alter for about 40 percent of the missing names. Other common answers, such as no "occasion... to be in touch," also suggest that the true rate of alters being dropped is probably under 20 percent. Multilevel logit models identified the predictors of alters being dropped (neither relisted nor forgotten) versus retained. Immediate kin were likeliest to be retained and roommates, coworkers, and acquaintances to be dropped. Alters who provided companionship, confiding, advice, and emergency help were especially likely to be retained, as were those to whom respondents felt close. Little about the respondents themselves affected drop rates: having moved recently, having a close friend die, or having had an important relationship break up. Results are consistent with the argument that a tie's degree of constraint (notably being close family) and its balance of rewards determine the likelihood of it being dropped or demoted.
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http://dx.doi.org/10.1016/j.socnet.2019.08.008 | DOI Listing |
Proc Natl Acad Sci U S A
February 2025
Forest Biology Center, Institute of Environmental Biology, Faculty of Biology, Adam Mickiewicz University, 61-614 Poznan, Poland.
Climate change is impacting forests in complex ways, with indirect effects arising from interactions between tree growth and reproduction often overlooked. Our 43-y study of European beech () showed that rising summer temperatures since 2005 have led to more frequent seed production events. This shift increases reproductive effort but depletes the trees' stored resources due to insufficient recovery periods between seed crops.
View Article and Find Full Text PDFFront Plant Sci
January 2025
Center of Molecular Ecophysiology (CMEP), College of Resources and Environment, Southwest University, Chongqing, China.
Introduction: The growth of evergreen fruit trees is influenced by the interaction of soil nitrogen (N) and leaf amino acid contents. However, information on free amino acid contents in leaves of fruiting and non-fruiting branches during long-term N fertilizer application remains scarce.
Methods: Here, a four-year field experiment (2018-2021) in a citrus orchard revealed consistently lower total N and amino acid contents in leaves of fruiting compared to non-fruiting branches.
Mol Cell Endocrinol
January 2025
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, USA; Reproductive Medicine Associates of New York, Department of Obstetrics, Gynecology and Reproductive Science, Division of Reproductive Endocrinology and Infertility, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
The purpose of this study was to examine the deposition of advanced glycation end products (AGEs) and their receptors, RAGE, in ovarian follicles during folliculogenesis in mice fed high (H-AGE) or low (L-AGE) AGE diets and following superovulation with gonadotropins. We hypothesize that H-AGE diet is associated with increased AGE deposition and RAGE expression in various stages of ovarian follicular development, and superovulation with gonadotropins may alter these changes. C57BL/6J mice were fed low L-AGE (n=10) or H-AGE (n=10) diet for 12 weeks.
View Article and Find Full Text PDFChin Med
January 2025
Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.
Background: Bear bile powder (BBP), a unique animal-derived medicine with anti-inflammatory and antioxidant effects, is used in Shexiang Tongxin dropping pills (STDP), which is applied to treat cardiovascular diseases, including acute myocardial infarction (AMI). The efficacy and compatibility mechanisms of action of BBP in STDP against cardiovascular diseases remain unclear. This study aimed to investigate the compatibility effects of BBP in STDP in rats with AMI.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Laboratory of Bioinformatics Applied to Health, Drug Research and Development Center (NPDM), Federal University of Ceará, Fortaleza, CE 60430-275, Brazil; Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Fortaleza, CE 60430-275, Brazil. Electronic address:
Colorectal cancer (CRC) affects the population worldwide, occupying the first place in terms of death and incidence. Synthetic peptides (SPs) emerged as alternative molecules due to their activity and low toxicity. Proteomic analysis of PepGAT-treated HCT-116 cells revealed a decreased abundance of proteins involved in ROS metabolism and energetic metabolisms, cell cycle, DNA repair, migration, invasion, cancer aggressiveness, and proteins involved in resistance to 5-FU.
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