: A Confirmed Calcifying Bacterium With a Potentially Important Role in the Supragingival Plaque.

is a reported calcifying bacterium that can usually be isolated from dental calculus and induce mineralization . In recent years, based on hybridization probe and sequencing technology, researchers have discovered the central "pillar" role of in supragingival plaque, and many studies focused on bacterial interactions in the biofilm structure dominated by have been conducted. Besides, seems to be an indicator of "caries-free" oral status according to imaging and sequencing studies. Therefore, in this review, we summarize 's role in supragingival plaque based on the structure, interactions, and potential connections with oral diseases.