Background And Aim: In Ayurveda, ashwagandha is a popular plant for promoting youthful energy, longevity, and overall well-being. It is also an excellent aphrodisiac herb that aids in the improvement and maintenance of normal sexual health. The present study aims to evaluate the effect of ashwagandha root extract on improving sexual health in adult males.
Methods: In this 8-week randomized, double-blind, placebo-controlled study, we investigated the aphrodisiac property of an ashwagandha root extract in adult males. Fifty participants with lower sexual desire were randomly allocated to take 300 mg of ashwagandha root extract or placebo capsules twice daily. Outcomes were measured using the derogatis interview for sexual functioning-male (DISF-M) questionnaire, serum testosterone, serum prolactin, and short-form survey-36 quality of life questionnaire before and after the intervention.
Results: Compared to placebo, ashwagandha root extract supplementation was associated with a statistically significant increase in the total DISF-M scores (mean difference -9.8; 95% confidence interval, -10.73 to -8.87; < 0.0001; -test). It was also associated with a statistically significant increase in serum testosterone levels (-66.52; -80.70 to -52.34; < 0.0001; -test). However, the prolactin level did not change after intervention in both the ashwagandha and placebo groups (-1.06; -2.78 to 0.66; > 0.05).
Conclusion: These findings suggest that ashwagandha demonstrated a significant subjective perception of sexual well-being and assisted in increasing serum testosterone levels in the participants.
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http://dx.doi.org/10.1002/hsr2.741 | DOI Listing |
Sci Rep
January 2025
Department of Clinical Biochemistry, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
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School of Information Science and Technology, Beijing University of Technology, Beijing 100124 China.
Carbon steel and low alloy steel are pearlitic heat-resistant steels with a lamellar microstructure. There are good mechanical properties and are widely used in crucial components of high-temperature pressure. However, long-term service in high-temperature environments can easily lead to material degradation, including spheroidization, graphitization, and thermal aging.
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January 2025
Department of Computer Science and Engineering, Sathyabama Institute of Science and Technology, Shollinganallur, Chennai, India.
Municipal waste classification is significant for effective recycling and waste management processes that involve the classification of diverse municipal waste materials such as paper, glass, plastic, and organic matter using diverse techniques. Yet, this municipal waste classification process faces several challenges, such as high computational complexity, more time consumption, and high variability in the appearance of waste caused by variations in color, type, and degradation level, which makes an inaccurate waste classification process. To overcome these challenges, this research proposes a novel Channel and Spatial Attention-Based Multiblock Convolutional Network for accurately classifying municipal waste that utilizes a unique attention mechanism for enhancing feature learning and waste classification accuracy.
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January 2025
Faculty of Pharmacy, University of Belgrade, 11221 Belgrade, Serbia.
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View Article and Find Full Text PDFPharmaceutics
January 2025
Department of Pharmacognosy and Biomaterials, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland.
This study explores the development of electrospun nanofibers incorporating bioactive compounds from (Ashwagandha) root extract, focusing on optimizing extraction conditions and nanofiber composition to maximize biological activity and application potential. Using the Design of Experiment (DoE) approach, optimal extraction parameters were identified as 80% methanol, 70 °C, and 60 min, yielding high levels of phenolic compounds and antioxidant activity. Methanol concentration emerged as the critical factor influencing phytochemical properties.
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