A transcription factor helps Plasmodium falciparum gametocytogenesis take shape.

Trends Parasitol

Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

Published: September 2022

AI Article Synopsis

  • A recent study by Campelo Morillo et al. found a unique non-ApiAP2 DNA-binding protein in Plasmodium falciparum.
  • This protein functions as a transcription factor during the process of gametocytogenesis.
  • It plays a crucial role in determining the distinctive shape and characteristics of the gametocyte.

Article Abstract

The recent study by Campelo Morillo et al. has shown that one of the small number of non-ApiAP2 DNA-binding proteins in the Plasmodium falciparum genome acts as a transcription factor in the gametocytogenesis cascade and is responsible for the gametocyte's distinctive morphology.

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Source
http://dx.doi.org/10.1016/j.pt.2022.07.004DOI Listing

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