Cryo-electron tomography: A long journey to the inner space of cells.

Cell

Max-Planck-Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany. Electronic address:

Published: July 2022

Cryogenic electron tomography (cryo-ET) is the application of tomographic principles of data acquisition and reconstruction to frozen-hydrated biological specimens. It combines a close-to-life preservation of cellular structures with the power of high-resolution three-dimensional imaging, which allows us to study the molecular architecture of cells, or their molecular sociology, in unprecedented detail.

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http://dx.doi.org/10.1016/j.cell.2022.06.034DOI Listing

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