AI Article Synopsis
- Cage compounds have customizable binding pockets resembling enzyme-binding sites that can be modified in size, shape, and functional groups.
- A variety of synthetic methods allow for the creation of specialized organic cages for diverse applications like gas separation, molecular recognition, and catalysis.
- The review highlights advancements in organic molecular cages, emphasizing their unique properties and capabilities for encapsulating guest molecules.
Article Abstract
Cage compounds offer unique binding pockets similar to enzyme-binding sites, which can be customized in terms of size, shape, and functional groups to point toward the cavity and many other parameters. Different synthetic strategies have been developed to create a toolkit of methods that allow preparing tailor-made organic cages for a number of distinct applications, such as gas separation, molecular recognition, molecular encapsulation, hosts for catalysis, etc. These examples show the versatility and high selectivity that can be achieved using cages, which is impossible by employing other molecular systems. This review explores the progress made in the field of fully organic molecular cages and containers by focusing on the properties of the cavity and their application to encapsulate guests.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413269 | PMC |
| http://dx.doi.org/10.1021/acs.chemrev.2c00198 | DOI Listing |
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