Homalolides C-D, two new sesquiterpenoids from the rhizomes of .

Two new sesquiterpenoids, homalolides C - D ‒, were co-isolated from the rhizomes of (Blume) Bakh.f collected in Vietnam with five known ones, aromadendrane-4,10-diol (), bullatantriol (), 1,4,6-trihydroxy-eudesmane (), 1,4,6-trihydroxyeudesmane (), and 1,4,7-trihydroxy-eudesmane (). The structures and relative configuration of new compounds were elucidated by 1 D-/2D-NMR, IR, UV and HRESIMS analyses, and by comparisons to the reported data in the literature. Homalolide C presented an unprecedented skeleton with the 4/8 bicyclic system. All isolates did not exhibit appreciable inhibitory effects on LPS-induced NO production in the RAW 264.7 macrophage cell line and on the growth of human lung cancer cell line (SK-LU-1).