Among 134 223 patients with coronavirus disease 2019 (COVID-19), we assessed how risk of hospitalization changed at different intervals in the pandemic, controlling for prior COVID-19 immunity. In multivariable analysis, outpatients with COVID-19 during the Omicron-predominant time period had significantly lower odds of hospitalization compared to pre-Delta (adjusted odds ratio, 0.26 [95% confidence interval, .22-.32]).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214143PMC
http://dx.doi.org/10.1093/ofid/ofac288DOI Listing

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