AI Article Synopsis
- Gallbladder cancer has a poor prognosis, and imaging methods like FDG-PET/CT have varying levels of diagnostic accuracy for this type of cancer.
- A retrospective study included 22 patients with suspected gallbladder cancer who underwent preoperative FDG-PET/CT, comparing their histological results.
- The results showed no significant ability of FDG-PET/CT to differentiate between malignant and benign cases, indicating that this imaging method is not reliable for confirming gallbladder cancer diagnosis.
Article Abstract
Gallbladder cancer has a poor prognosis and imaging can have variable diagnostic accuracy. We assessed the ability of preoperative F-fluorodeoxyglucose positron emission tomography computed tomography ( F-FDG-PET/CT) imaging to predict a postoperative histological diagnosis of gallbladder cancer. A retrospective analysis was undertaken in a cohort of patients, who had suspected gallbladder cancer on cross-sectional imaging and that underwent preoperative FDG-PET/CT scan. The discriminatory power of FDG-PET/CT was determined in receiver operator characteristic (ROC) analysis and diagnostic accuracy parameters were estimated at different thresholds of maximum standard unit value (SUV ) Twenty-two patients were included in the study; 7 had malignant and 15 benign diagnoses. There was no statistically significant difference between the measured SUV between the two groups ( = 0.71). With an area under the curve of 0.486, the ROC curve did not indicate any discriminatory power of FDG-PET/CT at any potential threshold of SUV This study indicates that the diagnosis of primary gallbladder cancer cannot be accurately confirmed with FDG PET/CT scanning.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296241 | PMC |
| http://dx.doi.org/10.1055/s-0042-1750332 | DOI Listing |
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