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Current approaches of nanomedicines in the market and various stage of clinical translation. | LitMetric

Current approaches of nanomedicines in the market and various stage of clinical translation.

Acta Pharm Sin B

State Key Laboratory of Drug Research & Center of Pharmaceutics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

Published: July 2022

AI Article Synopsis

  • - Nanomedicines offer superior therapeutic efficiency, lower toxicity, and targeted delivery compared to traditional drug therapies, making them a promising option in medicine.
  • - The review highlights various nanomedicines currently in use or clinical trials, showcasing diverse carrier types, applications, and mechanisms for treating diseases such as cancer, infections, and cardiovascular issues.
  • - The article also discusses future research and development considerations to enhance the clinical implementation of nanomedicines.

Article Abstract

Compared with traditional drug therapy, nanomedicines exhibit intriguing biological features to increase therapeutic efficiency, reduce toxicity and achieve targeting delivery. This review provides a snapshot of nanomedicines that have been currently launched or in the clinical trials, which manifests a diversified trend in carrier types, applied indications and mechanisms of action. From the perspective of indications, this article presents an overview of the applications of nanomedicines involving the prevention, diagnosis and treatment of various diseases, which include cancer, infections, blood disorders, cardiovascular diseases, immuno-associated diseases and nervous system diseases, etc. Moreover, the review provides some considerations and perspectives in the research and development of nanomedicines to facilitate their translations in clinic.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293719PMC
http://dx.doi.org/10.1016/j.apsb.2022.02.025DOI Listing

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