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| http://dx.doi.org/10.18502/ijph.v51i3.8952 | DOI Listing |
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Transcriptional regulation of Cry2Ab toxin receptor ABCA2 gene in insects involves GATAe and splicing of a 5' UTR intron.
Pestic Biochem Physiol
December 2024
School of Life Sciences, Central China Normal University, Wuhan 430070, China. Electronic address:
Bacillus thuringiensis (Bt) produces Cry toxins that are used to control insect pests worldwide. However, evolution of insect resistance threatens the sustainable application of these toxins. In some cases, Cry toxin resistance has been linked to mutations affecting toxin receptors expression.
View Article and Find Full Text PDFImpact of Propofol Administered before Extubation on Respiratory Adverse Events in Pediatric Patients Undergoing Tonsillectomy and Adenoidectomy: A Randomized Controlled Trial.
Br J Hosp Med (Lond)
November 2024
Department of Anesthesiology, Children's Hospital of Fudan University, Shanghai, China.
Perioperative respiratory adverse events (PRAEs) are common in pediatric anesthesia, especially in otolaryngology procedures. In this randomized controlled trial, we investigated the impact of administering propofol before extubation on PRAEs in pediatric patients undergoing tonsillectomy and adenoidectomy. We enrolled children aged 3 to 8 years old, of American Society of Anesthesiologists (ASA) classes I to III, scheduled for tonsillectomy, and randomly divided them into propofol and control groups.
View Article and Find Full Text PDFThe antidepressant-like effects of kisspeptin-10 are reversed by kisspeptin antagonist peptide 234 in male rats.
Cell Mol Biol (Noisy-le-grand)
November 2024
Department of Physiology, Medical School, Istanbul Okan University, Istanbul, Turkey.
Kisspeptins are reported to be the most potent activators of the hypothalamus-pituitary-gonadal (HPG) axis known to date. Kisspeptin potently elicits gonadotropin-releasing hormone (GnRH) release and luteinizing hormone (LH) secretion, even in the pre-pubertal period. Beyond the hypothalamus, kisspeptin is also expressed in limbic and paralimbic brain regions, which are areas of the neurobiological network primarily implicated in emotional behaviors alongside sexual functions.
View Article and Find Full Text PDFThe acoustic properties, syllable structure, and syllable sequences of ultrasonic vocalizations (USVs) during neonatal opioid withdrawal in FVB/N mouse substrains.
bioRxiv
November 2024
Laboratory of Addiction Genetics, Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA USA.
Concomitant with the opioid epidemic, there has been a rise in pregnant women diagnosed with opioid use disorder and cases of infants born with neonatal opioid withdrawal syndrome (NOWS). NOWS refers to signs and symptoms following cessation of prenatal opioid exposure that comprise neurological, gastrointestinal, and autonomic system dysfunction. A critical indicator of NOWS severity is excessive, high-pitched crying.
View Article and Find Full Text PDFComparison of different techniques used for inferior alveolar nerve block anaesthesia regarding the pain caused in cooperative children.
Eur Arch Paediatr Dent
November 2024
Faculty of Dentistry, Department of Paediatric Dentistry, Pamukkale University, Kınıklı, Denizli, Turkey.
Purpose: The aim of this study is to compare the application of inferior alveolar nerve block (IANB) anaesthesia in children with traditional plastic syringe (TPS) and computer-controlled injection device Dentapen using two different modes [continuous mode (DC) and ramp-up mode (DR)] in terms of pain.
Methods: This study included 96 children aged 7-12 who were determined to be positive (3) or definitely positive (4) according to the Frankl Behaviour Evaluation Scale and in need of treatment who had IANB anaesthesia indication in the right and left regions. Patients were divided into three groups and compared in terms of pain felt during IANB anaesthesia according to heart rate, oxygen saturation, Wong Baker Pain Rating Scale, Face Legs Activity Cry Consolability Pain Scale and patient preference distributions.
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