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| http://dx.doi.org/10.1016/j.hrcr.2022.05.004 | DOI Listing |
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Omnipolar mapping versus point-by-point mapping approach for catheter ablation of atrioventricular accessory pathway.
J Interv Card Electrophysiol
January 2025
Department of Cardiovascular Medicine, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsugagun, Tochigi, 321-0293, Japan.
Background: The conventional mapping approach for the atrioventricular accessory pathway (AP) involves point-by-point mapping to identify the connection sites of the AP to the atria or ventricle and accurate interpretation of local electrograms. Omnipolar mapping technology (OMT) explains how vector and wave speed are produced by using both unipolar and bipolar signals to obtain omnipolar signals, directions, and conduction velocity. The aim of this study is to verify the effectiveness of OMT for catheter ablation of AP.
View Article and Find Full Text PDFPredictive coding in neuropsychiatric disorders: a systematic transdiagnostic review.
Neurosci Biobehav Rev
January 2025
Department of Brain and Behavioral Sciences, University of Pavia, Italy. Electronic address:
The predictive coding framework postulates that the human brain continuously generates predictions about the environment, maximizing successes and minimizing failures based on prior experiences and beliefs. This PRISMA-compliant systematic review aims to comprehensively and transdiagnostically examine the differences in predictive coding between individuals with neuropsychiatric disorders and healthy controls. We included 72 case-control studies investigating predictive coding as the primary outcome and reporting behavioral, neuroimaging, or electrophysiological findings.
View Article and Find Full Text PDFPeak Frequency Analysis and Functional Substrate Mapping to Predict Critical Isthmus of Atypical Atrial Tachycardia; Findings from a Novel Automated Annotation Algorithm to Detect Near Field Signals.
Heart Rhythm
January 2025
Hacettepe University, Faculty of Medicine, Department of Cardiology, Ankara, Turkey.
Background: Atypical atrial tachycardia (AT) is a commonly encountered rhythm disorder especially in patients with underlying atrial scar. Peak frequency (PF) annotation of bipolar electrograms is a novel method, which mainly aims to discriminate near-field and far-field signals.
Objective: To evaluate the association between PF annotation of low-voltage zones (LVZ) and deceleration zones (DZ) during sinus / paced rhythm and their role to predict the critical isthmus (CI) and termination sites of atypical ATs.
Synaptic protein expression in bipolar disorder patient-derived neurons implicates PSD-95 as a marker of lithium response.
Neuropharmacology
January 2025
Department of Psychiatry and Center for Circadian Biology, University of California San Diego, La Jolla, CA, USA; VA San Diego Healthcare System, San Diego, CA, USA. Electronic address:
Bipolar disorder (BD) is a severe mental illness characterized by recurrent episodes of depression and mania. Lithium is the gold standard pharmacotherapy for BD, but outcomes are variable, and the relevant therapeutic mechanisms underlying successful treatment response remain uncertain. To identify synaptic markers of BD and lithium response, we measured the effects of lithium on induced pluripotent stem cell-derived neurons from BD patients and controls.
View Article and Find Full Text PDFLeft Bundle Branch Area Pacing Compared to Right Ventricular Outflow Tract Septal Pacing: Mid-term Results and Learning Curve.
J Innov Card Rhythm Manag
December 2024
Arrhythmia Unit, Department of Cardiology, University Hospital Clinico Lozano Blesa, Zaragoza, Spain.
Our study evaluated the efficacy and feasibility of left bundle branch area pacing (LBBAP) compared to right ventricular outflow tract septal pacing (RVOSP). We conducted a prospective, single-center, observational study involving 200 consecutive patients who required pacemaker implantation. The patients were divided into two groups (LBBAP and RVOSP), with 100 patients in each group.
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