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Post-intrathecal chemotherapy-related paraplegia syndrome in hematological cancer patients: A systematic review.
Neurooncol Adv
December 2024
Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
Background: Intrathecal (IT) chemotherapy is essential in treating hematological malignancies, but it can lead to ascending paraplegia, a condition that currently lacks clear management guidelines.
Methods: We conducted a systematic review, analyzing 1219 studies and 116 patients, adhering to PRISMA guidelines for individual patient data. The study, registered under PROSPERO (CRD42022362121), focused on the onset, diagnostic approaches, and therapeutic interventions associated with this complication, and management strategies to tackle the ascending paraplegia.
Postoperative paraplegia due to spinal cord infarction after tricuspid valve replacement.
Kardiochir Torakochirurgia Pol
December 2024
Department of Cardiothoracic Surgery, General Hospital of Thessaloniki "G. Papanikolaou", Thessaloniki, Greece.
"Ear of the Lynx" Sign in Hereditary Spastic Paraplegia 76.
J Clin Neurol
January 2025
Department of Neurology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine and Biomedical Research Institute, Yangsan, Korea.
A Novel Crossover between Vici Syndrome and Spastic Paraplegia: Variant of EPG5 in Spastic Paraplegia.
Indian J Pediatr
January 2025
Child Neurology Division, Department of Pediatrics, All India Institute of Medical Sciences, Bathinda, Punjab, India.
Intradural extramedullary tuberculoma in a case of disseminated tuberculosis: A case report.
Surg Neurol Int
December 2024
Department of Orthopedics, KEM Hospital and Seth GS Medical College, Mumbai, Maharashtra, India.
Background: Intradural extramedullary tuberculoma of the spinal cord (IETSC) is an exceedingly rare manifestation of tuberculosis (TB) affecting the central nervous system.
Case Description: A 33-year-old immunocompetent female with disseminated TB, including pulmonary involvement and leptomeningeal tuberculomas, developed progressive paraplegia and urinary incontinence over 2 months. Magnetic resonance imaging revealed diffuse intradural extramedullary soft tissue from C7 to L2 vertebral levels, indicative of abscess formation and severe spinal cord compression.
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