AI Article Synopsis
- Teratocarcinosarcoma affecting the anterior skull base is rare and challenging to treat due to its invasive nature, but the endoscopic endonasal approach (EEA) shows promise for surgical intervention.
- A case study details a 50-year-old man with a significant lesion at the anterior skull base, which was successfully removed using EEA, along with reconstruction of the skull base.
- Utilizing EEA for such tumors can be effective, but thorough reconstruction and lumbar drainage can help reduce the risk of complications like cerebrospinal fluid leaks.
Article Abstract
Background: Teratocarcinosarcoma traversing the anterior skull base is rarely reported in literature. The heterogenous and invasive features of the tumor pose challenges for surgical planning. With technological advancements, the endoscopic endonasal approach (EEA) has been emerging as a workhorse of anterior skull base lesions. To date, no case has been reported of EEA totally removing teratocarcinosarcomas with intracranial extensions.
Observations: The authors provided an illustrative case of a 50-year-old otherwise healthy man who presented with left-sided epistaxis for a year. Imaging studies revealed a 31 × 60-mm communicating lesion of the anterior skull base. Gross total resection via EEA was achieved, and multilayered skull base reconstruction was performed.
Lessons: The endoscopic approach may be safe and effective for resection of extensive teratocarcinosarcoma of the anterior skull base. To minimize the risk of postoperative cerebrospinal fluid leaks, multilayered skull base reconstruction and placement of lumbar drainage are vitally important.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281494 | PMC |
| http://dx.doi.org/10.3171/CASE21471 | DOI Listing |
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