AI Article Synopsis
- Herpes zoster (HZ) is caused by the reactivation of the varicella-zoster virus and is more common in immunocompromised individuals, such as cancer patients.
- HZ can lead to long-lasting complications that negatively affect treatment for cancer and quality of life.
- A new recombinant zoster vaccine offers strong immune responses for immunocompromised patients, prompting the need for guidelines on HZ vaccination recommendations for cancer patients.
Article Abstract
Herpes zoster (HZ) is the infectious reactivation of the varicella-zoster virus. HZ is more frequent in immunocompromised subjects, including patients with cancer. HZ complications can even last for years with a consequent delay in treatment of the underlying malignancy and with an unfavorable impact on quality of life. Nowadays, HZ is a vaccine-preventable disease: the recent approval of adjuvanted glycoprotein E-based recombinant zoster vaccine has changed preventive perspectives in immunocompromised subjects. Recombinant zoster vaccine induced both strong humoral and cellular immune responses also in immunocompromised patients. The question is, therefore, to which categories of cancer patients we should recommend HZ vaccination. Based on a careful review of the available data present in the literature, including recommendations and expert opinions, we report the position of the Associazione Italiana di Oncologia Medica on HZ vaccination in adult patients with solid tumors, thus providing clinical practice advice in a field where clear-cut information is missing.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434335 | PMC |
| http://dx.doi.org/10.1016/j.esmoop.2022.100548 | DOI Listing |
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