Objectives: To determine if a digital communication app improves care timelines for patients with suspected acute stroke/ST-elevation myocardial infarction (STEMI).
Design: Real-world feasibility study, quasi-experimental design.
Setting: Prehospital (25 Ambulance Victoria branches) and within-hospital (2 hospitals) in regional Victoria, Australia.
Participants: Paramedics or emergency department (ED) clinicians identified patients with suspected acute stroke (onset <4.5 hours; n=604) or STEMI (n=247).
Intervention: The Pulsara communication app provides secure, two-way, real-time communication. Assessment and treatment times were recorded for 12 months (May 2017-April 2018), with timelines compared between 'Pulsara initiated' (Pulsara) and 'not initiated' (no Pulsara).
Primary Outcome Measure: Door-to-treatment (needle for stroke, balloon for STEMI) Secondary outcome measures: ambulance and hospital processes.
Results: Stroke (no Pulsara n=215, Pulsara n=389) and STEMI (no Pulsara n=76, Pulsara n=171) groups were of similar age and sex (stroke: 76 vs 75 years; both groups 50% male; STEMI: 66 vs 63 years; 68% and 72% male). When Pulsara was used, patients were off ambulance stretcher faster for stroke (11(7, 17) vs 19(11, 29); p=0.0001) and STEMI (14(7, 23) vs 19(10, 32); p=0.0014). ED door-to-first medical review was faster (6(2, 14) vs 23(8, 67); p=0.0001) for stroke but only by 1 min for STEMI (3 (0, 7) vs 4 (0, 14); p=0.25). Door-to-CT times were 44 min faster (27(18, 44) vs 71(43, 147); p=0.0001) for stroke, and percutaneous intervention door-to-balloon times improved by 17 min, but non-significant (56 (34, 88) vs 73 (49, 110); p=0.41) for STEMI. There were improvements in the proportions of patients treated within 60 min for stroke (12%-26%, p=0.15) and 90 min for STEMI (50%-78%, p=0.20).
Conclusions: In this Australian-first study, uptake of the digital communication app was strong, patient-centred care timelines improved, although door-to-treatment times remained similar.
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http://dx.doi.org/10.1136/bmjopen-2021-052332 | DOI Listing |
Nat Commun
December 2024
Department of Civil and Environmental Engineering, and Research Centre for Resources Engineering towards Carbon Neutrality, The Hong Kong Polytechnic University, Hong Kong, China.
The feasibility of carbon mineralization relies on the carbonation efficiency of CO-reactive minerals, which is largely governed by the water content and state within material mesopores. Yet, the pivotal role of confined water in regulating carbonation efficiency at the nanoscale is not well understood. Here, we show that the maximum CO intake occurs at an optimal relative humidity (RH) when capillary condensation initiates within the hydrophilic mesopores.
View Article and Find Full Text PDFSci Rep
December 2024
Clean Energy Technologies Research Institute (CETRI), Process Systems Engineering, Faculty of Engineering & Applied Science, University of Regina, 3737 Wascana Parkway, Regina, SK, S4S 0A2, Canada.
Real-world emissions of particulate matter (PM) and smoke opacity were studied for an older-model diesel pickup truck during four types of driving tests, namely fixed-point test, snap-acceleration test, road test, and hill road test (uphill/downhill). A portable emissions measurement system (PEMS) and an opacimeter were used to measure real-time concentrations of PM and smoke opacity, respectively, and simultaneously. Correlation analysis showed a significant positive association between PM and opacity, suggesting the feasibility of using an opacimeter to estimate PM mass emissions from diesel vehicles.
View Article and Find Full Text PDFPediatr Rheumatol Online J
December 2024
Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, 686 Bay Street, Room 06.9715, Toronto, ON, M5G 0A4, Canada.
Background: Juvenile Idiopathic Arthritis (JIA) is a chronic pediatric illness, whereby youth experience physical, emotional and psychosocial challenges that result in reduced health related quality of life (HRQL). Peer mentoring has been shown to improve disease self-management in adults with chronic conditions, with mixed results in younger populations. Building on our pilot work - which supported the feasibility and initial effectiveness of the iPeer2Peer program - the objective of this study was to assess the clinical effectiveness of the program in youth with JIA through a waitlist randomized controlled trial.
View Article and Find Full Text PDFBMC Pediatr
December 2024
Department of Paediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Copenhagen, Denmark.
Background: Many children and adolescents with cerebral palsy (CP) experience cognitive difficulties, impacting their academic, social, and emotional well-being. A Danish study from 2023 revealed that merely 40% of individuals with CP complete their elementary school education, and previous neuropsychological studies have found that most children and adolescents with CP experience cognitive difficulties. Yet, cognitive functioning is often assumed rather than assessed, and CP follow-up programs focus predominantly on physical functioning.
View Article and Find Full Text PDFBMJ Open
December 2024
Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.
Introduction: Children represent a large and vulnerable patient group. However, the evidence base for most paediatric diagnostic and therapeutic procedures remains limited or is often inferred from adults. There is an urgency to improve paediatric healthcare provision based on real-world evidence generation.
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