[Textual research on Wumei Pills].

Zhongguo Zhong Yao Za Zhi

Graduate School, China Academy of Chinese Medical Sciences Beijing 100700, China.

Published: July 2022

AI Article Synopsis

  • Wumei Pills is derived from the Treatise on Cold Damage, with extensive analysis encompassing its origins, composition, uses, contraindications, and modern clinical applications based on 128 historical and contemporary records.
  • The formulation consists of various herbs, including Mume Fructus and Ginseng, and is indicated for multiple ailments such as digestive issues, nervous system disorders, and certain metabolic conditions, with evolving application over time.
  • Despite a decrease in dosage from the Han to Qing Dynasty, the proportions of the ingredients remained constant, highlighting the need for careful medicinal selection and processing for safety, particularly regarding certain components that may be toxic.

Article Abstract

Wumei Pills originates from Treatise on Cold Damage. A total of 128 records on it were screened out, involving 102 ancient books, 110 modern clinical studies, and 48 diseases. According to the records, the prescription origin, prescription composition, prescription explanation, main indications, dosage, medicinal processing, preparation, and usage, contraindications, and mo-dern clinical applications were analyzed. The result shows that Wumei Pills is composed of Mume Fructus, Asari Radix et Rhizoma, Zingiberis Rhizoma, Coptidis Rhizoma, Angelicae Sinensis Radix, Aconiti Lateralis Radix Praeparata, Zanthoxyli Pericarpium, Cinnamomi Ramulus, Ginseng Radix et Rhizoma, and Phellodendri Chinensis Cortex. The main indications expand over time, and it can be applied to diarrhea, dysentery, retching, chest pain, cough, Qi ascending from lower abdomen, and reversal cold of hands and feet with the syndromes of cold and heat in complexity and hyperactivity of liver Yang and spleen deficiency. According to modern clinical records, it is mainly used for the treatment of diseases in the digestive system, nervous system, endocrine system, metabolic system, etc., such as ulcerative colitis, diarrhea, insomnia, and type 2 diabetes mellitus. The dosage of Wumei Pills has gradually reduced from the Han Dynasty to the Qing Dynasty, but the proportions of the medicinals has remained basically unchanged. In this prescription, Aconiti Lateralis Radix Praeparata and Zanthoxyli Pericarpium need to be processed, while the rest medicinals are used in raw form. As for the medicinal selection, Zanthoxyli Pericarpium is examinable. Asari Radix et Rhizoma is derived from Aristolochiaceae, which is toxic to the liver and kidney, so the dosage should be kept in a safe range. In summary, Wumei Pills has great clinical value. The textual research on Wumei Pills helps clarify the development of Wumei Pills, which provides evidence in-depth research and development and rational clinical application of Wumei Pills.

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http://dx.doi.org/10.19540/j.cnki.cjcmm.20220427.501DOI Listing

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