In silico chromosome painting is a technique by which contributions of distinct genetic groups are represented along chromosomes of hybrid individuals. This type of analysis is used to study the mechanisms by which these individuals were formed. Such techniques are well adapted to identify genetic groups contributing to these individuals as well as hybridization events. It can also be used to follow chromosomal recombinations that occurred naturally or were generated by selective breeding. Here, we present GeMo, a novel interactive web-based and user-oriented interface to visualize in a linear-based fashion results of in silico chromosome painting. To facilitate data input generation, a script to execute analytical commands is provided and an interactive data curation mode is supported to ensure consistency of the automated procedure. GeMo contains preloaded datasets from published studies on crop domestication but can be applied to other purposes, such as breeding programs Although only applied so far on plants, GeMo can handle data from animals as well. Database URL: https://gemo.southgreen.fr/.
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http://dx.doi.org/10.1093/database/baac057 | DOI Listing |
Int J Mol Sci
December 2024
College of Jixian Honors, Zhejiang Agriculture and Forestry University, Hangzhou 311300, China.
Heat stress transcription factors (HSFs) play a critical role in orchestrating cellular responses to elevated temperatures and various stress conditions. While extensively studied in model plants, the gene family in remains unexplored, despite the availability of its sequenced genome. In this study, we employed bioinformatics approaches to identify 21 genes within the genome, revealing their uneven distribution across chromosomes.
View Article and Find Full Text PDFMed Oncol
January 2025
Department of Medical Surgical Nursing, College of Nursing, Princess Nourah bint Abdulrahman University, P.O. Box 84428, 11671, Riyadh, Saudi Arabia.
CRC has the third-highest cancer incidence and death. Many human cancers, including colorectal cancer, are connected to abnormal signaling pathway gene expression. Many human malignancies include Hippo and Rap1 signaling.
View Article and Find Full Text PDFSci Rep
January 2025
Microbiology Division, Defence Research and Developmental Establishment, Jhansi Road, Gwalior, 474002, India.
Yersinia pestis, a Gram-negative bacterium is the causative agent of the fatal communicable disease plague. The disease had a profound impact on human history. Plague bacteria are usually transmitted to humans through the bite of an infected rat flea.
View Article and Find Full Text PDFPlants (Basel)
December 2024
Scientific Observing and Experimental Station of Maize in Plain Area of Southern Region, Ministry of Agriculture and Rural Affairs, School of Life Sciences, Nantong University, Nantong 226019, China.
β-ketoacyl-CoA synthase (KCS) enzymes play a pivotal role in plants by catalyzing the first step of very long-chain fatty acid (VLCFA) biosynthesis. This process is crucial for plant development and stress responses. However, the understanding of genes in maize remains limited.
View Article and Find Full Text PDFAnimals (Basel)
December 2024
Department of Poultry Breeding, Animal Production Research Institute, Agriculture Research Center, Dokki, Giza 12618, Egypt.
This study aimed to characterize microsatellites in the rabbit genome using an in silico approach and to develop and validate microsatellite markers. Blood samples were collected from 15 Baladi rabbits and 18 New Zealand White (NZW rabbits). The GMATA software was used to define SSRs in the extracted sequences.
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