Two new monoterpene esters ( and ) and four known compounds (-) were isolated from the pericarps of . Their structures were elucidated by extensive spectroscopic analyses and their anti-inflammatory activity was evaluated by monitoring their inhibitory effects on the interleukin-1-induced production of nitric oxide in primary cultured rat hepatocytes. The new compound and cardamonin showed inhibitory activities with IC values of 17.6 ± 1.1 and 10.2 ± 1.3 µM, respectively, which are comparable to that of the positive control N-methyl-L-arginine acetate salt.
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http://dx.doi.org/10.1080/14786419.2022.2101053 | DOI Listing |
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