The present study harnesses fluorescence quenching between a nonfluorescent aniline and fluorophore 2-acetyl-3-benzo[]chromen-3-one [2AHBC] in binary solvent mixtures of acetonitrile and 1,4-dioxane at room temperature and explores the fluorophore as an antimicrobial material. Our findings throw light on the key performance of organic molecules in the medicinal and pharmaceutical fields, which are considered as the most leading drives in therapeutic applications. In view of that, fluorescence quenching data have been interpreted by various quenching models. This demonstrates that the sphere of action holds very well in the present work and also confirms the presence of static quenching reactions. Additionally, the fluorophore was first investigated for druglike activity with the help of tools, and then it was investigated for antimicrobial activity through bioinformatics tools, which has shown promising insights.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280945 | PMC |
| http://dx.doi.org/10.1021/acsomega.2c02424 | DOI Listing |
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